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IFNAR2 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16816963 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16816963 20 μL 20µL
16806963 150 μL 150µL
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Product Code. 16816963 Supplier Proteintech Supplier No. 105221AP20UL

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Description

Rabbit Polyclonal Antibody

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.

Specifications

Antigen IFNAR2
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IFNAR2
Gene Accession No. P48551
Gene Alias IFN alpha REC, IFN alpha/beta receptor 2, IFN R, IFN R 2, IFNABR, IFNAR2, IFNARB, Type I interferon receptor 2
Gene Symbols IFNAR2
Host Species Rabbit
Immunogen IFNAR2 Fusion Protein Ag0191
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3455
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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