IFN-γ Mouse anti-Human, PE, Clone: 4S.B3, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 561056

Product Code. 15840729

Description

The 4S.B3 monoclonal antibody specifically binds to interferon-γ(IFN-γ). The immunogen used to generate this hybridoma was partially purified human IFN-γobtained from supernatants of human PBMC stimulated with Staphylococcus aureus . Interferon-γ(IFN-γ) is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γexerts its biological effects through specific binding to the high-affinity IFN-γReceptor Complex comprised of IFN-γRα (CD119) and ese influences can involve IFN- γ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γis a 14- 18 kDa glycoprotein containing 143 amino acid residues.

Specifications

• Antigen: IFN-γ
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human IFN-γ from supernatants of S. aureus-stimulated PBMC
• Quantity: 25 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 4S.B3
• Conjugate: PE
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.