IFN-alpha 2 Antibody (N39), PE/Cy5.5, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-54398PECY55

Product Code. 18262652

Description

IFN-alpha 2 Monoclonal specifically detects IFN-alpha 2 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: IFN-alpha 2
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: IFNA2
• Immunogen: Purified recombinant human IFN-alpha 2 (Uniprot: P01563)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This monoclonal antibody is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this monoclonal antibody is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 monoclonal antibodys are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: N39
• Dilution: Flow Cytometry
• Gene Alias: alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Apoptosis, Biologically Active Proteins, Cytokine Research
• Gene ID (Entrez): 3440.0
• Target Species: Human
• Isotype: IgG1 κ