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IFITM3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16898973 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
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16898973 20 μL 20µL
16888973 150 μL 150µL
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Product Code. 16898973 Supplier Proteintech Supplier No. 117141AP20UL

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Description

Rabbit Polyclonal Antibody

11714-1-AP is a rabbit polyclonal antibody raised against the full-length of human IFITM3.

IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.

Specifications

Antigen IFITM3
Applications Immunohistochemistry (Paraffin), Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunofluorescence
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene IFITM3
Gene Accession No. P26376, Q01628, Q9CQW9
Gene Alias 1 8U, Fragilis, IFITM3, IP15
Gene Symbols Ifitm3
Host Species Rabbit
Immunogen IFITM3 Fusion Protein Ag2285
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10410, 361673, 66141
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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