Invitrogen™ IFITM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA524701

Product Code. 13291669

Description

IFITM2 Polyclonal Antibody for Western Blot, IHC (P)

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Specifications

• Antigen: IFITM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IFITM2
• Gene Alias: 1-8D; dispanin subfamily A member 2c; DSPA2c; IFITM2; ifm2; interferon induced transmembrane protein 2; interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q01629
• Gene Symbols: IFITM2
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human IFM2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG