IDO Mouse anti-Human, PE, Clone: eyedio, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9477-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15557206

Quantity Price
1 £ 84.7 / 25 tests
EU Stock 2
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Description and Specification

Specification

Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Gene Alias Indoleamine-2,3-dioxygenase
Species Reactivity Human
Antigen IDO
Quantity 25 tests
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone eyedio
Conjugate PE
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry (Intracellular Staining)
Format Conjugated
Concentration 5μL (0.06μg)/test

This eyedio monoclonal antibody reacts with human indoleamine-2,3-dioxygenase (IDO, INDO, IDO1), an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells.