IDH3G Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA551668

Product Code. 15769620

Description

Immunogen sequence: ADEEDIRNAI MAIRRNRVAL KGNIETNHNL PPSHKSRNNI LRTSLDLYAN VIHCKSLPGV VTRHKDIDIL IVRENTEGEY SSLEHESVAG VVESLKIITK AKSLRIAEYA FKLAQESGRK KVTAVHKANI MKLGDGLFLQ CCREVAA Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Specifications

• Antigen: IDH3G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Idh3g
• Gene Alias: H-IDHG; IDH; IDH3G; IDH-gamma; iso; Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) gamma; isocitrate dehydrogenase 3 (NAD), gamma; isocitrate dehydrogenase 3 (NAD+) gamma; isocitrate dehydrogenase 3 (NAD+), gamma; isocitrate dehydrogenase 3 gamma; isocitrate dehydrogenase 3, gamma; isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit; isocitric dehydrogenase subunit gamma; NAD (H)-specific isocitrate dehydrogenase gamma subunit; NAD(+)-specific ICDH subunit gamma; NAD+-isocitrate dehydrogenase gamma subunit; NAD+-specific ICDH
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15929, 25179, 3421
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P41565, P51553, P70404
• Gene Symbols: Idh3g
• Immunogen: Recombinant protein corresponding to Human IDH3G
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Research Use Only