Invitrogen™ IDH3A Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142769

Product Code. 17858642

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Specifications

• Antigen: IDH3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IDH3A
• Gene Alias: 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; H-IDH alpha; Idh3a; isocitrate dehydrogenase (NAD(+)) 3 alpha; isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) alpha; isocitrate dehydrogenase 3 (NAD+) alpha; isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 100157242, 114096, 3419, 67834
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P50213, P56471, Q99NA5, Q9D6R2
• Gene Symbols: IDH3A
• Immunogen: Peptide with sequence DFTEEICRRVKDLD (aa 353-366).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Pig
• Product Type: Antibody
• Isotype: IgG