Invitrogen™ ICOS (CD278) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA579432

Product Code. 15915005

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: mouse stomach tissue, mouse spleen tissue, mouse thymus tissue, mouse small intestine tissue, rat thymus tissue, human placenta tissue. IHC: mouse spleen tissue, mouse thymus tissue, rat spleen tissue.

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

Specifications

• Antigen: ICOS (CD278)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ICOS
• Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29851, 54167, 64545
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: Q9R1T7, Q9WVS0, Q9Y6W8
• Gene Symbols: ICOS
• Immunogen: E. coli-derived mouse ICOS recombinant protein (Position: E21-S200).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG