Invitrogen™ ICK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551513

Product Code. 15749470

Description

Immunogen sequence: VGHPLGSTTQ NLQDSEKPQK GILEKAGPPP YIKPVPPAQP PAKPHTRISS RQHQASQPPL HLTYPYKAEV SRTDHPSHLQ EDKPSPLLFP SLHNKHPQSK ITAGLEHKNG EIKPKSRRR Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 63%.

ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems.

Specifications

• Antigen: ICK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CILK1
• Gene Alias: 2210420N10Rik; AI848300; ciliogenesis associated kinase 1; CILK1; ECO; heart serine-threonine protein kinase; hICK; iciliogenesis associated kinase 1; ICK; intestinal cell (MAK-like) kinase; intestinal cell kinase; KIAA0936; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; mICK; MRK; serine/threonine protein kinase; serine/threonine-protein kinase ICK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22858
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UPZ9
• Gene Symbols: CILK1
• Immunogen: Recombinant protein corresponding to Human ICK. Recombinant protein control fragment (Product #RP-93677).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG