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Tocris Bioscience™ ICA 069673
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Product Code. 18717046
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25 mg
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18717046 25 mg 25mg
18795356 5 mg 5mg
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Product Code. 18717046 Supplier Tocris Bioscience™ Supplier No. 4305/25

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Description

KV7.2/KV7.3 channel opener

ICA 069673 is a selective KV7.2/KV7.3 (KCNQ2/3) channel opener (EC50 = 0.69 μM). Exhibits 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. Hyperpolarizes resting membrane potential and inhibits spontaneous action potentials in guinea pig detrusor muscle (DSM) isolated cells. Orally active in animal models of epilepsy.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide
CAS 582323-16-8
Assay Percent Range >99%
Quantity 25 mg
Molecular Formula C11H6ClF2N3O
Formula Weight Observed MW: 269.63
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