Invitrogen™ IBTK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561733

Product Code. 15749541

Description

Immunogen sequence: ILFVTQDGEG FRGRWFEEKR KSSEKKEILS NLHNSSSDVS YVSDINSVYE RIRLEKLTFA HRAVSVSTDP SGCNFAILQS DPKTSLYEIP AVSSSSFFEE FGKLLREADE MDSIHDVTFQ VGN Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.

The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.

Specifications

• Antigen: IBTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IBTK
• Gene Alias: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; IBTK; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; KIAA1417; RP1-93K22.1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25998
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9P2D0
• Gene Symbols: IBTK
• Immunogen: Recombinant protein corresponding to Human IBTK. Recombinant protein control fragment (Product #RP-103025).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG