Invitrogen™ IBSP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA541327

Product Code. 15554772

Description

Peptide sequence: SATTLGYGED ATPGTGYTGL AAIQLPKKAG DITNKATKEK ESDEEEEEEE Sequence homology: Dog: 79%; Human: 100%.

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Specifications

• Antigen: IBSP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ibsp
• Gene Alias: BNSP; Bone sialoprotein 2; bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; integrin-binding sialoprotein; SP-II
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3381
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P21815
• Gene Symbols: Ibsp
• Immunogen: Synthetic peptide directed towards the N-terminal of human IBSP (aa 108-157).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG