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Iberdomide, MedChemExpress

Product Code. 16492716
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Product Code. 16492716

Brand: Medchem Express HY101291

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Description

MedChemExpress Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ∼150 nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities.

Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ∼150 nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities.

Specifications

Chemical Name or Material Iberdomide
CAS 1323403-33-3
Color White
Purity Grade Notes Research
Molecular Formula C25H27N3O5
Quantity 25 mg
Synonym CC-220
Solubility Information DMSO : 125 mg/mL (278.09 mM; Need ultrasonic)
SMILES O=C([C@@H](N(CC1=C2C=CC=C1OCC3=CC=C(CN4CCOCC4)C=C3)C2=O)CC5)NC5=O
Molecular Weight (g/mol) 449.5
Formula Weight 449.5
Percent Purity 98.03%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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