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  8. IACS-010759 hydrochloride, MedChemExpress

IACS-010759 hydrochloride, MedChemExpress

Product Code. 16495396
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Product Code. 16495396 Supplier Medchem Express Supplier No. HY112037A

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Description

MedChemExpress IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research.

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research.

Specifications

Chemical Name or Material IACS-010759 hydrochloride
CAS 1807523-99-4
Color White
Purity Grade Notes Research
Molecular Formula C25H26ClF3N6O4S
Quantity 100 mg
Synonym IACS-10759 hydrochloride
Solubility Information DMSO : 60 mg/mL (100.16 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES FC(F)(F)OC1=CC=C(C2=NOC(C3=NN(CC4=CC(N5CCC(S(=O)(C)=O)CC5)=CC=C4)C(C)=N3)=N2)C=C1.Cl
Molecular Weight (g/mol) 599.02
Formula Weight 599.02
Percent Purity 98.91%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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