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I-BET282, MedChemExpress

Product Code. 16473837
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Product Code. 16473837 Supplier Medchem Express Supplier No. HY19760

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Description

MedChemExpress I-BET282 is a pan-inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC50s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD).

I-BET282 is a pan-inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC50s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD).

Specifications

Chemical Name or Material I-BET282
CAS 1422554-34-4
Color White
Purity Grade Notes Research
Molecular Formula C25H30N4O4
Quantity 50 mg
Solubility Information DMSO : 100 mg/mL (221.96 mM; Need ultrasonic)
SMILES COC1=C(C2=C(C)ON=C2C)C=C(N=CC3=C4N(C(C5CCOCC5)=N3)[C@@H](COC)C)C4=C1
Molecular Weight (g/mol) 450.53
Formula Weight 450.53
Percent Purity 99.12%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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