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Tocris Bioscience™ I 432

Product Code. 18766606
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5 mg
Unit Size:
5mg
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Product Code. 18766606 Supplier Tocris Bioscience™ Supplier No. 7292/5

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Description

TMPRSS2 Inhibitor

I 432 is a TMPRSS2 (transmembrane serine proteinase 2) inhibitor (Ki =0.9 nM). It blocks influenza virus propagation in airway epithelial cells. In IPEC-J2 pig jejunal epithelial cells, I 432 (50 μM) inhibits TMPRSS2 without affecting cell viability after 48 h treatment.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-[(2 S)-3-[4-(2-Aminoethyl)-1-piperidinyl]-2-[[(2 ',4 '-dichloro[1,1 '-biphenyl]-3-yl)sulfonyl]amino]-3-oxopropyl]benzenecarboximidamide ditrifluoroacetate
CAS 1268874-09-4
Quantity 5 mg
Target TMPRSS2
Molecular Formula C29H33Cl2N5O3S0.2 CF3CO2H
Purity 0.98
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