Hypericin, 98%, Thermo Scientific™

Hypericin, CAS # 548-04-9, is an anthraquinone derivative that shows antidepressant, antiviral, antineoplastic, and immunostimulant activities.

Brand:  Thermo Scientific Alfa Aesar H26425.MC

Product Code. 11466440

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Hypericin is an anthraquinone derivative found in the yellow flower of Hypericum perforatum (also known as St. John's wort)
• This compound has the ability to inhibit protein kinase C, inducing photosynthesized apoptosis

Application

• It shows antibiotic and antiviral activities
• The antidepressant activity of this compound could be related to its ability to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine, gamma-aminobutyric acid (GABA), and L-glutamate
• Since this compound is able to inhibit the assembly and shedding of virus particles in infected cells, hypericin may also prevent the replication of encapsulated viruses
• It has been described that this compound can also exhibit anti-HIV and anticancer activities
• Hypericin also displays an effective phototoxic activity and is able to trigger apoptotic pathways, resulting in the formation of reactive oxygen species

Chemical Identifiers

• CAS: 548-04-9
• Molecular Weight (g/mol): 504.45
• InChI Key: BTXNYTINYBABQR-UHFFFAOYSA-N
• PubChem CID: 5281051
• SMILES: CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O

• Molecular Formula: C30H16O8
• MDL Number: MFCD00016683
• Synonym: hypericin, hypericum red, hipericina, hypericine, hyperizin, cyclosan, 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro 1,10,9,8-opqra perylene-7,14-dione, cyclo-werol, hypericum extract, vimrxyn
• ChEBI: CHEBI:5835

Specifications

• CAS: 548-04-9
• MDL Number: MFCD00016683
• Beilstein: 1917913
• Merck Index: 14,4863
• Solubility Information: Soluble in ethanol,dimethyl sulfoxide,methanol,acetone,ethylmethylketone,pyridine and sodium hydroxide. Insoluble in water.
• SMILES: CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
• PubChem CID: 5281051
• Formula Weight: 504.44
• Chemical Name or Material: Hypericin

• Molecular Formula: C30H16O8
• Quantity: 100mg
• Sensitivity: Light sensitive
• Synonym: hypericin, hypericum red, hipericina, hypericine, hyperizin, cyclosan, 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro 1,10,9,8-opqra perylene-7,14-dione, cyclo-werol, hypericum extract, vimrxyn
• InChI Key: BTXNYTINYBABQR-UHFFFAOYSA-N
• Molecular Weight (g/mol): 504.45
• ChEBI: CHEBI:5835
• Percent Purity: 98%