Thermo Scientific Chemicals Hydrocortisone, 98%

Product Code.	Quantity	Packaging	unitSize
10062031	1 g	Glass bottle	1g
10738372	5 g	Glass bottle	5g
10560794	25 g	Glass bottle	25g
10209703	100 g	Glass bottle	100g

Product Code. 10062031 Supplier Thermo Scientific Chemicals Supplier No. 352450010

Description

Hydrocortisone, CAS # 50-23-7, is the pharmaceutical formulation of the hormone, cortisol, and is commonly administered as an immunosuppressive drug.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Hydrocortisone is the synthetic formulation of the naturally occurring hormone, cortisol
• It is available as a white crystalline powder soluble in water, DMSO, and ethanol
• It is stable at room temperature but sensitive to light, and reactive in the presence of strong oxidizing agents

Applications

• Hydrocortisone works as an agonist to glucocorticoid receptors, thereby suppressing the inflammatory response of the immune system
• It’s administration induces gluconeogenesis, thus increasing endogenous blood sugar levels
• Research indicates a role for hydrocortisone in the metabolism of fat, protein, and carbohydrates

Specifications

Chemical Identifiers

• CAS: 50-23-7
• Molecular Formula: C₂₁H₃₀O₅
• Molecular Weight (g/mol): 362.47
• MDL Number: MFCD00011654
• InChI Key: JYGXADMDTFJGBT-VWUMJDOOSA-N
• Synonym: hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril
• PubChem CID: 5754
• ChEBI: CHEBI:17650
• IUPAC Name: (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
• SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

• Melting Point: 212°C to 217°C
• Color: White
• Infrared Spectrum: Authentic
• Assay Percent Range: 97.5% min. (HPLC)
• Packaging: Glass bottle
• Quantity: 1 g
• Merck Index: 15, 4824
• Specific Rotation Condition: +150° (156°C c=1,dioxane)
• Specific Rotation: + 150
• Solubility Information: Solubility in water: 0.28g/L (25°C). Other solubilities: soluble in sulfuric acid,partially soluble in alcohol and propylene glycol,soluble in dioxane; sol (g/l) (25°C): chcl3 1.6;,ether 0.35; etoh 15; meoh 6.2; acetone 9.3;,propylene glycol 1
• Formula Weight: 362.47
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: Hydrocortisone

Safety and Handling

Product Identifier

• Hydrocortisone

Signal Word

• Warning

Hazard Category

• Reproductive toxicity Category 2

Hazard Statement

• H361f-Suspected of damaging fertility.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS

RUO – Research Use Only