Invitrogen™ HYD Recombinant Rabbit Monoclonal Antibody (24GB2540)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30276336	Invitrogen™ MA557826	100 μL
30276311	Invitrogen™ MA557827	20 μL

Description

HYD Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

EDD (for E3 identified by Differential Display) is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Specifications

• Antigen: HYD
• Concentration: 1.2 mg/mL
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O95071, Q62671, Q80TP3
• Gene ID (Entrez): 117060, 51366, 70790
• Immunogen: A synthesized peptide derived from human EDD (aa 1-54).
• Product Type: Antibody

• Clone: 24GB2540
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: UBR5
• Gene Alias: CH D1S3362; DD5; E3 identified by differential display; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; ECGF1; Edd; Edd1; EDG1; EDG-1; extraembryonic development; HECT-type E3 ubiquitin transferase UBR5; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; Progestin-induced protein; Rat100; S1P receptor 1; S1P receptor Edg-1; S1P1; S1PR1; ubiquitin protein ligase E3 component n-recognin 5; Ubr5
• Gene Symbols: UBR5
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography