Invitrogen™ HYAL3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550427

Product Code. 15674355

Description

The antibody detects endogenous levels of total HYAL3 protein.

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Specifications

• Antigen: HYAL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HYAL3
• Gene Alias: Hyal3; hyal-3; Hyaluronidase; hyaluronidase 3; hyaluronidase-3; hyaluronoglucosaminidase 3; hyaluronoglucosaminidase-3; Hyl3; LUCA14; LUCA3; LuCa-3; Lung carcinoma protein 3; Minna14
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8372
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O43820
• Gene Symbols: HYAL3
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human hyaluronoglucosaminidase 3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG