hVEGF-IN-1, MedChemExpress

Product Code. 16466377

Brand: Medchem Express HY101931

Description

MedChemExpress hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a Kd of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression.

hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a Kd of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression.

Specifications

• Chemical Name or Material: hVEGF-IN-1
• CAS: 1637443-98-1
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₃₄H₄₃N₇O₂
• Quantity: 5 mg
• Solubility Information: DMSO : 25 mg/mL (42.97 mM; Need ultrasonic)
• SMILES: CCN(CC)CCOC(C=C1)=CC=C1NC2=NC(C3=C(NC(CCN4CCN(C)CC4)=O)C=CC=C3)=NC5=CC=CC=C52
• Molecular Weight (g/mol): 581.75
• Formula Weight: 581.75
• Percent Purity: 98.56%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only