Invitrogen™ HUS1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576200

Product Code. 15962725

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Specifications

• Antigen: HUS1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hus1b
• Gene Alias: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint clamp component B; HUS1 checkpoint homolog b; HUS1 checkpoint homolog b (S. pombe); Hus1 homolog b (S. pombe); Hus1b; MGC126746; MGC126748; mHUS1B; RP11-532F6.1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135458, 210554, 691382
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8K572, Q8NHY5
• Gene Symbols: Hus1b
• Immunogen: Recombinant fusion protein of human HUS1B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG