Proteintech HumanKine™ recombinant human IL-8 protein

Product Code. 17680077

Brand: Proteintech HZ131810UG

Description

HumanKine™ recombinant protein

IL-8 is a chemoattractant cytokine that signals through the CXCR1 and CXCR2 receptors to attract and activate neutrophils to sites of inflammation. It is secreted by multiple types of cells, including monocytes, neutrophils, tumor, epithelial, endothelial, and fibroblasts. IL-8 signaling activates downstream pathways that promote cell survival, proliferation, and cell invasiveness. As such, IL-8 has been linked to the promotion of angiogenesis, immunosuppressive cell recruitment, and EMT transition in several cancer types. Recent studies also indicate that IL-8 can serve as a marker for COVID-19 disease progression (PMID: 22235381, 18980965, 26548401, 33584733).

Specifications

• Accession Number: P10145
• Formulation: 1 x PBS
• Gene ID (Entrez): 3576
• Molecular Weight (g/mol): 12 kDa
• Quantity: 10 μg
• Source: HEK293
• Storage Requirements: Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
• Endotoxin Concentration: <0.1 EU/μg
• Specific Reactivity: Human
• Recombinant: Recombinant
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
• Form: Lyophilized
• Purity or Quality Grade: >95%