Proteintech HumanKine™ recombinant human IL-34 protein

Product Code. 17620077

Brand: Proteintech HZ131610UG

Description

HumanKine™ recombinant protein

IL-34 is a 6-α-helix, proinflammatory cytokine that serves as a ligand for colony-stimulating factor-1 receptor (CSF1R). It is expressed most abundantly by spleen cells. It primarily stimulates human peripheral blood monocyte proliferation and macrophage colony formation. It is also required for Langerhans cell and microglia development. IL-34 has been shown to play a protective role in cancer and Alzheimer’s disease, but it can promote the progression of several autoimmune, inflammatory, and metabolic diseases. As such IL-34 could be used as a biomarker to mark the progression of these diseases (PMID: 22579672, 27577879, 31940023).

Specifications

• Accession Number: Q6ZMJ4
• Formulation: 50 mM Acetate pH 4.5 + 75 mM NaCl, See Certificate of Analysis for details
• Gene ID (Entrez): 146433
• Molecular Weight (g/mol): 68 and 38 kDa
• Quantity: 10 μg
• Source: HEK293
• Storage Requirements: Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
• Endotoxin Concentration: <1 EU/μg
• Specific Reactivity: Human
• Recombinant: Recombinant
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
• Form: Lyophilized
• Purity or Quality Grade: >95%