Invitrogen™ Human WWP1 (aa 98-193) Control Fragment Recombinant Protein

Product Code. 30207930

Brand: Invitrogen™ RP93779

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54715 (PA5-54715. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq].

Specifications

• Accession Number: Q9H0M0
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 11059
• Name: Human WWP1 (aa 98-193) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 8030445B08Rik; AIP5; atrophin-1 interacting protein 5; atrophin-1-interacting protein 5; DKFZp434D2111; HECT-type E3 ubiquitin transferase WWP1; hSDRP1; NEDD4-like E3 ubiquitin-protein ligase WWP1; Nedd-4-like ubiquitin-protein ligase; SDRP1; TGIF-interacting ubiquitin ligase 1; Tiul1; Unknown (protein for MGC:129005); WW domain containing E3 ubiquitin protein ligase 1; WW domain-containing protein 1; Wwp1
• Common Name: WWP1
• Gene Symbol: Wwp1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: TIDLKQALLIHNRKLERVKEQLKLSLENKNGIAQTGELTVVLDGLVIEQENITNCSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGIDNHV
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining