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Gibco™ Human VEGF-C Recombinant Protein, PeproTech®

Product Code. 17811643
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Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
5µg
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Product Code. 17811643

Brand: Gibco™ 10020CD100UG

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Description

Recombinant Protein

Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49767
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 7424
Molecular Weight (g/mol) 26.2 kDa
Name Human VEGF-C
Quantity 100 μg
Source HEK293 cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias AW228853; Flt4 ligand; FLT4 ligand DHM; Flt4-L; LMPH1D; Vascular endothelial growth factor C; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; vascular endothelial growth factor-related protein; VEGF3; VEGFC; VEGF-C; VRP
Common Name VEGFC
Gene Symbol VEGFC
Biological Activity Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions.
Conjugate Unconjugated
Recombinant Recombinant
Sequence AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
Content And Storage -20°C
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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