Invitrogen™ Human USP12 (aa 152-175) Control Fragment Recombinant Protein

Product Code. 30195704

Brand: Invitrogen™ RP108970

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139844 (PA5-139844. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt]

Specifications

• Accession Number: O75317
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 219333
• Name: Human USP12 (aa 152-175) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: Deubiquitinating enzyme 12; UBH1; Ubiquitin carboxyl-terminal hydrolase 12; ubiquitin hydrolyzing enzyme 1; ubiquitin specific peptidase 12; ubiquitin specific protease 12; ubiquitin specific protease 12 like 1; ubiquitin thioesterase 12; ubiquitin thiolesterase 12; ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12; Usp12; USP12L1
• Common Name: USP12
• Gene Symbol: USP12
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RLPNGNIDNENNNSTPDPTWVHEI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining