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Invitrogen™ Human Ubinuclein 2 (aa 1245-1346) Control Fragment Recombinant Protein

Product Code. 30194891
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Quantity:
100 μL
Unit Size:
100µL
This item is not returnable. View return policy

Product Code. 30194891

Brand: Invitrogen™ RP92771

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54071 (PA5-54071. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6ZU65
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 254048
Name Human Ubinuclein 2 (aa 1245-1346) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2900060J04Rik; 6030408G03Rik; BC060116; D130059P03Rik; Kiaa2030; mKIAA2030; ubinuclein 1; ubinuclein 2; ubinuclein-2; UBN1; UBN2; VT; VT4
Common Name Ubinuclein 2
Gene Symbol UBN2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SVTNQNVTPFGMLGGLVPVTMPFQFPLEIFGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGGAQHAATLSHSPLPAHLQQAFHDGGQSKGDTKLPRKS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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