Invitrogen™ Human TSSC4 (aa 163-249) Control Fragment Recombinant Protein

Product Code. 30196068

Brand: Invitrogen™ RP97525

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (66%), Rat (66%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59737 (PA5-59737. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TSSC4 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Accession Number: Q9Y5U2
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10078
• Name: Human TSSC4 (aa 163-249) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AA241958; ESTM671070; MNCb-3063; Protein TSSC4; Tssc4; tumor suppressing subtransferable candidate 4; tumor-suppressing STF cDNA 4 protein; tumor-suppressing subchromosomal transferable fragment 4; tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein
• Common Name: TSSC4
• Gene Symbol: TSSC4
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: TKYSLEDVTEVSEQSNQATALAFLGSQSLAAPTDCVSSFNQDPSSCGEGRVIFTKPVRGVEARHERKRVLGKVGEPGRGGLGNPATD
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining