Invitrogen™ Human TSPAN32 (aa 237-314) Control Fragment Recombinant Protein

Product Code. 30198566

Brand: Invitrogen™ RP90918

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82869 (PA5-82869. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Specifications

• Accession Number: Q96QS1
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10077
• Name: Human TSPAN32 (aa 237-314) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AML1-regulated transmembrane protein 1; ART1; Art-1; AW208513; BB235973; D7Wsu37e; FLJ17158; FLJ97586; MGC22455; pan hematopoietic expression; pan-hematopoietic expression protein; Phemx; PHMX; protein Phemx; tetraspanin; tetraspanin 32; tetraspanin-32; TSPAN32; Tspan-32; Tssc6; tumor-suppressing STF cDNA 6; tumor-suppressing subchromosomal transferable fragment 6; tumor-suppressing subchromosomal transferable fragment cDNA 6; tumor-suppressing subtransferable candidate 6
• Common Name: TSPAN32
• Gene Symbol: TSPAN32
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: LTPRACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHRALQGRSRGGLSGCP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining