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Invitrogen™ Human TRPML1 (aa 105-192) Control Fragment Recombinant Protein

Product Code. 30196103
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30196103

Brand: Invitrogen™ RP109189

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Defects in Mucolipin-1 are the cause of mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9GZU1
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 57192
Name Human TRPML1 (aa 105-192) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2210015I05Rik; MCLN1; Mcoln1; MCOLN1 mucolipin 1; MG-2; MGC7172; ML1; ML4; MLIV; MST080; MSTP080; Mucolipidin; mucolipidosis type IV protein; mucolipin 1; mucolipin-1; Transient receptor potential channel mucolipin 1; Transient receptor potential-mucolipin 1; TRPML1; TRP-ML1; TRPM-L1
Common Name TRPML1
Gene Symbol MCOLN1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence FLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDC
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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