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Invitrogen™ Human TRIM25 Synthetic Peptide

Product Code. 15358650
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. 15358650

Brand: Invitrogen™ PEP0527

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This item is not returnable. View return policy

Description

Synthetic Peptide

TRIM25 Synthetic Peptide, PEP-0527, from Invitrogen.

TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation. TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s. Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 7706
Species Human
Purification Method purified
Accession Number Q14258
Common Name Human TRIM25
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol TRIM25
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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