Invitrogen™ Human TREM-1 Recombinant Protein

Product Code. 11519051

Brand: Invitrogen™ RP75732

Description

Recombinant Protein

This product contains purified recombinant human TReM1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.

Specifications

• Accession Number: Q9NP99
• Concentration: 0.25 mg/mL
• For Use With (Application): Control, Western Blot
• Formulation: 10 mM tris HCl with 50% glycerol, 62.5 mM NaCl and no preservative; pH 8
• Gene ID (Entrez): 54210
• Molecular Weight (g/mol): 24.76 kDa
• Name: Human TREM-1
• pH Range: 8
• Quantity: 1 mg
• Source: E. coli
• Immunogen: N/A
• Regulatory Status: RUO
• Gene Alias: CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
• Common Name: TREM1
• Gene Symbol: TREM1
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Amino acids Ala21-Arg200 containing an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions