Invitrogen™ Human TP53I11 (aa 82-101) Control Fragment Recombinant Protein

Product Code. 30194413

Brand: Invitrogen™ RP101957

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63770 (PA5-63770. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

Specifications

• Accession Number: O14683
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 9537
• Name: Human TP53I11 (aa 82-101) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: p53-induced gene 11 protein; Pig11; TP53I11; transformation related protein 53 inducible protein 11; Trp53i11; tumor protein p53 inducible protein 11; tumor protein p53-inducible protein 11
• Common Name: TP53I11
• Gene Symbol: TP53I11
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: AFPDQLYDAVFDGAQVTSKT
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining