Invitrogen™ Human TMEM185A (aa 128-148) Control Fragment Recombinant Protein

Artikelnummer. 30193586

Brand: Invitrogen™ RP105659

Beskrivelse

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84873 (PA5-84873. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013].

Tekniske data

• Accession Number: Q8NFB2
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 84548
• Name: Human TMEM185A (aa 128-148) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: BC023829; cDNA sequence BC023829; CXorf13; Ee3; erythropoietin-induced EST 3; FAM11A; family with sequence similarity 11, member A; fragile site, folic acid type, rare, fra(X)(q28) F; FRAXF; Protein FAM11A; Tmem185a; transmembrane protein 185 A
• Common Name: TMEM185A
• Gene Symbol: TMEM185A
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: AACVWGFRHDRSLELEILCSV
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining