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Invitrogen™ Human TM4SF1 Synthetic Peptide
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Quantity:
50 μg
Unit Size:
50µg
Description
TM4SF1 Synthetic Peptide, PEP-1233, from Invitrogen.
TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
Specifications
Specifications
| Gene ID (Entrez) | 4071 |
| Species | Human |
| Purification Method | purified |
| Accession Number | P30408 |
| Common Name | Human TM4SF1 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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