Invitrogen™ Human TLX2 (aa 1-20) Control Fragment Recombinant Protein

Product Code. 30211619

Brand: Invitrogen™ RP107150

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66477 (PA5-66477. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.

Specifications

• Accession Number: O43763
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 3196
• Name: Human TLX2 (aa 1-20) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: Enteric neuron homeobox protein; Enx; homeo box 11-like 1; homeobox 11-like1; homeobox protein Hox-11L1; Homeobox TLX-2; ho x 11 L; Ho x 11 L0.1; Ho x 11l1; NCX; Nc x 1; neural crest homeobox protein; PMUR10F; T cell leukemia homeobox 2; T cell leukemia, homeobox 2; T-cell leukemia associated homeodomain protein; T-cell leukemia associated homeodomain protein Tl x 3 A; T-cell leukemia homeobox 2; T-cell leukemia homeobox protein 2; T-cell leukemia, homeobox 2; T-cell leukemia, homeobox 3 A; Tl x 1l1; Tl x 1l2; Tl x 2; tl x 3 A; Tlx-3 A; tlxA; transcription factor
• Common Name: TLX2
• Gene Symbol: TLX2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: MEPGMLGPHNLPHHEPISFG
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining