Invitrogen™ Human TIM-4 ELISA Kit

Sandwich ELISA Kit

Brand:  Invitrogen™ EH455RBX10

Product Code. 17787803

Description

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Specifications

• Accession Number: Q96H15
• Assay Sensitivity: 20 pg/mL
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene Symbol: TIMD4
• Intraassay CV: <10%
• Label or Dye: HRP
• Regulatory Status: RUO
• Storage Requirements: 2°C to 8°C
• Test Time: 1 hr 20 min

• Assay Range: 20 to 5,000 pg/mL
• Conjugate: Biotin
• Sample Type: Plasma, Serum, Supernatant
• Gene ID (Entrez): 91937
• Interassay CV: <12%
• Kit Contents: Pre-coated 96 well plate|Standard|Assay Diluent concentrate|Biotinylated Detection Antibody|SAV-HRP|Wash Buffer|Chromogen|Stop Solution|Adhesive Plate Covers
• Quantity: 10 x 96 Tests
• Sample Volume: Serum, 50 μL|Supernatant, 50 μL|Plasma, 50 μL
• Target: TIM-4 (TIMD4)
• Total Assay Time: 4 hr 45 min