Invitrogen™ Human TIM-4 ELISA Kit

Human TIM-4 quantitates human TIM-4 in serum, plasma, supernatant.

Product Code	Brand	Quantity
17175239	Invitrogen™ EH455RBX5	5 x 96 Tests
17144763	Invitrogen™ EH455RB	96 Tests

Description

Human TIM-4 quantitates human TIM-4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TIM-4.

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Spécification

• Accession Number: B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
• Assay Sensitivity: 20 pg/mL
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene Symbol: TIMD4
• Intraassay CV: <10%
• Label or Dye: HRP
• Sample Volume: Serum, 50 μL; Supernatant, 50 μL; Plasma, 50 μL
• Target: TIM-4 (TIMD4)
• Total Assay Time: 4 hr 45 min

• Assay Range: 20 to 5,000 pg/mL
• Conjugate: Biotin
• Sample Type: Plasma, Serum, Supernatant
• Gene ID (Entrez): Q96H15
• Interassay CV: <12%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Regulatory Status: Research Use Only
• Storage Requirements: 2°C to 8°C
• Test Time: 1 hr 20 min