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Invitrogen™ Human TIAF1 Synthetic Peptide
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Quantity:
50 μg
Unit Size:
50µg
Description
TIAF Synthetic Peptide, PEP-1581, from Invitrogen.
TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.
Specifications
Specifications
| Gene ID (Entrez) | 9220 |
| Species | Human |
| Purification Method | purified |
| Accession Number | O95411 |
| Common Name | Human TIAF1 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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