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Invitrogen™ Human TESPA1 (aa 142-230) Control Fragment Recombinant Protein

Product Code. 30208792
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208792

Brand: Invitrogen™ RP110088

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145202 (PA5-145202. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number A2RU30
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 9840
Name Human TESPA1 (aa 142-230) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 5830405N20Rik; A430001F24Rik; AI450549; HSPC257; KIAA0748; LOW QUALITY PROTEIN: protein TESPA1; protein TESPA1; TESPA1; thymocyte expressed; thymocyte expressed, positive selection associated 1; thymocyte-expressed positive selection-associated protein 1
Common Name TESPA1
Gene Symbol TESPA1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence GTNKTSSSISEILDKVQEDAEDVLFSLGFGQEDHKDTSRIPARFFTTPSQAKGIDFQLFLKSQVRRIEMEDPCLMLASRFKQVQTLAVT
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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