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Invitrogen™ Human TAS2R41 (aa 66-86) Control Fragment Recombinant Protein

Product Code. 30208033
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208033

Brand: Invitrogen™ RP101629

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (52%), Rat (52%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63394 (PA5-63394. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily. TAS2R41 is expressed mainly in taste receptor cells of the tongue and the palate eptithelia. Structurally, the TAS2R41 gene encodes a seven trans-membrane receptor protein and is clustered together with eight other taste receptor genes on chromosome 7. The compound chloramphenicol is an agonist for the TAS2R41 protein. Further, TAS2R41 may play a role in sensing the chemical composition of the gastrointestinal content. The activity of TAS2R41 may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2R41 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P59536
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 259287, 266656
Name Human TAS2R41 (aa 66-86) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias MGC119928; MGC119929; mGR26; mt2r35; T2R12; T2R26; T2R41; T2R59; Tas2r12; Tas2r126; Tas2r26; Tas2r41; taste 2 receptor member 41; taste receptor rT2R12; taste receptor type 2 member 41; Taste receptor type 2 member 59; taste receptor, type 2, member 126; taste receptor, type 2, member 41
Common Name TAS2R41
Gene Symbol TAS2R12P, TAS2R41
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence NFYYSAQKVEYSGGLGRQFFH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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