Invitrogen™ Human SS18 (aa 227-255) Control Fragment Recombinant Protein

Product Code. 30212574

Brand: Invitrogen™ RP101319

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63167 (PA5-63167. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.

Specifications

• Accession Number: Q15532
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 6760
• Name: Human SS18 (aa 227-255) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to x chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to x chromosome; synovial sarcoma-associated Ss18-alpha; SYT
• Common Name: SS18
• Gene Symbol: SS18
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: GQQPPMGMMGQVNQGNHMMGQRQIPPYRP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining