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Invitrogen™ Human SPTY2D1 (aa 164-241) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58760 (PA5-58760. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). Modulates RNA polymerase 1-mediated transcription. Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
Specifications
Specifications
| Accession Number | Q68D10 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 144108 |
| Name | Human SPTY2D1 (aa 164-241) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | DKFZp686I068; FLJ39441; Protein KU002155; Protein SPT2 homolog; Spt2; SPT2 chromatin protein domain containing 1; SPT2 domain-containing protein 1; SPT2, Suppressor of Ty, domain containing 1; SPTY2D1 |
| Common Name | SPTY2D1 |
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