Invitrogen™ Human SPANXD (aa 62-86) Control Fragment Recombinant Protein

Product Code. 30212566

Brand: Invitrogen™ RP108618

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (44%), Rat (44%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84932 (PA5-84932. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014].

Specifications

• Accession Number: Q9BXN6
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 64648
• Name: Human SPANXD (aa 62-86) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: cancer/testis antigen 11.4; cancer/testis antigen family 11, member 4; CT11.4; dJ171K16.1; Nuclear-associated protein SPAN-Xd; nuclear-associated protein SPAN-Xe; SPANX family member D; SPANX family, member D; SPANX family, member E; SPANX-C; SPANXD; SPANX-D; SPANXE; SPANX-E; Sperm protein associated with the nucleus on the x chromosome D; sperm protein associated with the nucleus, x chromosome, family member D; sperm protein associated with the nucleus, x chromosome, family member E
• Common Name: SPANXD
• Gene Symbol: SPANXD
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: TSPEELVNDHARKNRINPLQMEEEE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining