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Gibco™ Human Sox2 Recombinant Protein, PeproTech®
Description
Recombinant Human Sox2 is a 34.3 kDa protein containing 317 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Specifications
Specifications
| Accession Number | P48431 |
| For Use With (Application) | Functional Assay |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 6657 |
| Molecular Weight (g/mol) | 34.3 kDa |
| Name | Human Sox2 |
| Quantity | 100 μg |
| Source | E. coli |
| Regulatory Status | RUO |
| Endotoxin Concentration | <1 EU/ μg |
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