Invitrogen™ Human SLC52A2 (aa 228-250) Control Fragment Recombinant Protein

Product Code. 30199653

Brand: Invitrogen™ RP104034

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (57%), Rat (57%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64086 (PA5-64086. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012].

Specifications

• Accession Number: Q9HAB3
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 79581
• Name: Human SLC52A2 (aa 228-250) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2010003P03Rik; BVVLS2; D15Ertd747e; G protein-coupled receptor 172 A; G protein-coupled receptor 172 B; GPCR41; GPCR42; Gpr172a; Gpr172b; hRFT3; mRFT1; PAR1; PAR2; PERV-A receptor 1; PERV-A receptor 2 homolog; PEVR1; Porcine endogenous retrovirus A receptor 1; porcine endogenous retrovirus A receptor 2; Porcine endogenous retrovirus A receptor 2 homolog; Protein GPR172A; Protein GPR172B; putative G-protein coupled receptor GPCR41; Rft1; RFT3; RFVT2; RGD1560410; riboflavin transporter 1; Riboflavin transporter 3; rRFT1; Slc52a2; solute carrier family 52 (riboflavin transporter), member 2; solute carrier family 52 member 2; solute carrier family 52, riboflavin transporter, member 2; solute carrier protein 52, member 2
• Common Name: SLC52A2
• Gene Symbol: SLC52A2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ELGSGLQVGAPGAEEEVEESSPL
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining