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Invitrogen™ Human SFRS15 (aa 1045-1143) Control Fragment Recombinant Protein

Product Code. 30203936
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30203936

Brand: Invitrogen™ RP91822

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54429 (PA5-54429. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O95104
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 57466
Name Human SFRS15 (aa 1045-1143) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AA517739; CTD-binding SR-like protein RA4; KIAA1172; pre-mRNA splicing SR protein rA4; SCAF4; serine/arginine-rich splicing factor 15; SFR15; SFRS15; splicing factor serine alanine 15; splicing factor, arginine/serine-rich 15; SRA4; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4; SR-related CTD associated factor 4; SR-related CTD-associated factor 4; Srsf15
Common Name SFRS15
Gene Symbol SCAF4
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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