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Invitrogen™ Human SDPR (aa 263-396) Control Fragment Recombinant Protein

Product Code. 30204583
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30204583

Brand: Invitrogen™ RP90829

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (72%), Rat (72%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O95810
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 8436
Name Human SDPR (aa 263-396) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias caveolae associated protein 2; caveolae-associated protein 2; cavin 2; CAVIN2; cavin-2; EMBL:AAH81956.1}; phosphatidylserine binding protein; phosphatidylserine-binding protein; PS-p68; SDPR; sdpr {ECO:0000312; SDR; serum deprivation response; serum deprivation response protein; serum deprivation-response protein
Common Name SDPR
Gene Symbol CAVIN2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence VSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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